Argonaute2 regulates the pancreatic {beta}-cell secretome
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چکیده
This research was originally published in Molecular & Cellular Proteomics. Tattikota, S.G. and Sury, M.D. and Rathjen, T. and Wessels, H.H. and Pandey, A.K. and You, X. and Becker, C. and Chen, W. and Selbach, M. and Poy, M.N. Argonaute2 regulates the pancreatic {beta}-cell secretome. Mol Cell Proteomics. 2013; 12: 1214-1225. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.
منابع مشابه
Argonaute2 regulates the pancreatic β-cell secretome.
Argonaute2 (Ago2) is an established component of the microRNA-induced silencing complex. Similar to miR-375 loss-of-function studies, inhibition of Ago2 in the pancreatic β-cell resulted in enhanced insulin release underlining the relationship between these two genes. Moreover, as the most abundant microRNA in pancreatic endocrine cells, miR-375 was also observed to be enriched in Ago2-associat...
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تاریخ انتشار 2017